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8 Signs of Folate Deficiency You Might Be Ignoring

Plus, how to add more of the B vitamin to your diet.


By Cassie Shortsleeve, Prevention

There’s a reason pregnant women are always told to load up on folate: getting enough of the vitamin helps prevent neural tube, brain, or spinal cord defects in babies.

But folate isn’t just important for those who have a little one on the way. Another name for vitamin B9—which naturally occurs in foods like dark leafy greens, asparagus, and Brussels sprouts—folate is vital for healthy cell growth, cell function, and red blood cell formation, explains Dara Godfrey, RD, a dietitian based in New York who specializes in prenatal, bariatric, and gastrointestinal nutrition. “If we don’t get in enough folate, our cells cannot make new DNA, divide, and multiply,” she says.

That’s why folate is particularly important for women during pregnancy, especially during the first trimester, a time of rapid cell division and DNA creation, says Torey Armul, RD, spokesperson for the Academy of Nutrition and Dietetics and specialist in maternal and prenatal nutrition.

Preggers or not, think of folate as something that simply helps your body run smoothly. “Our bodies are creating DNA and making new cells all the time just to stay healthy,” says Armul.

Problem is, your body doesn’t make folate on its own, so you need to take it in through foods or supplementation. When you don’t get enough of the stuff, deficiency can crop up and cause a slew of unpleasant symptoms. Here’s how to tell if you need more of the vitamin in your diet, whether or not you really need to worry about deficiency, and how to ensure you’re filling up on folate.


What are the symptoms of folate deficiency?

The biggest sign of folate deficiency is megaloblastic anemia, a condition in which the body has a low number of abnormally large red blood cells, according to the National Institutes of Health (NIH). If you’re lacking in folate, your red blood cell count can go down because you’re inhibiting proper DNA synthesis. This can deprive your tissues of oxygen, leading to the following symptoms:
  • Weakness, fatigue, and irritability
  • Headaches
  • Shortness of breath
  • Problems with concentration
The cells in your mouth and those of your skin turn over frequently, notes Armul, so it’s also common to see the first signs of folate deficiency with the following:
  • Shallow sores in your mouth or on your tongue
  • Discoloration or paleness of the skin
  • Discoloration of the nails
  • Premature gray hair
Talk to your doctor if you’re experiencing several of the symptoms above. While lots of health conditions can cause headaches and fatigue, your MD can perform a blood test to confirm a folate deficiency.


But do you really need to be worried about folate deficiency?

Folate deficiency isn’t all that common, says Armul, especially if you eat a variety of nutrient-dense foods. The Centers for Disease Control and Prevention (CDC) estimates less than 1 percent of the population is truly deficient in folate.

However, some people are at higher risk for folate deficiency than others. Those who suffer from alcoholism, for example, tend to simply not eat enough and might have impaired systems—say, a liver that can’t function properly—that can mess with proper digestion and absorption of nutrients, says Armul.

“People with GI issues including celiac disease and inflammatory bowel disease (IBD) are also at higher risk for folate deficiency, due to an increased chance of nutrient malabsorption,” adds Godfrey.

Women in the early stages of pregnancy can also be at risk for getting inadequate amounts of folate, in part because when you’re pregnant, your need for folic acid goes up (growing baby!) while your appetite can go down, notes Armul.


How to get enough folate

The average adult needs 400 micrograms (mcg) of folate a day, according to the NIH. For the most part, the average person doesn’t need a supplement. “Foods and nutrients interact with each other, so if you are eating more leafy greens, you’re also increasing other nutrients and your fiber, which is good for your GI tract. The benefits just grow and grow if you take a food first approach,” says Armul.

Breakfast cereals and flour products like bread, pasta, and rice can also be enriched with folic acid, the synthetic form of folate found in supplements or fortified foods (just double check the nutrition label!).

If you are pregnant (or even thinking about becoming pregnant) you should get 600 mcg of folate per day. “The pregnant body needs folate immediately, on day one of pregnancy,” says Armul. “If a growing embryo does not have enough folic acid, the brain and spinal cord growth can be impaired early on.”

It can be hard to get 600 mcg of folate through food alone, so The American College of Obstetricians and Gynecologists suggests most women who are pregnant or planning to be should pop a vitamin containing folic acid. As a general rule of thumb, make sure to touch base with your doctor before reaching for a supplement.

While the NIH recommends getting no more than 1,000 mcg of folate per day, it is difficult to overdo it. Because it’s a water-soluable vitamin, your body will get rid of the excess through your urine, so “it’s very rare to get too much folate,” says Armul.


See more at: Prevention

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Health Magazine: 8 Signs of Folate Deficiency You Might Be Ignoring
8 Signs of Folate Deficiency You Might Be Ignoring
Experts explain if you need more folate in your diet, if you really need to worry about folate deficiency, and how to eat more of it in your diet.
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